… Rabbit polyclonal anti-H3 antibody (#9715) was from Cell Signaling Technology.
Mouse monoclonal antibody against GST (A00865) was from GenScript Corporation.
Mouse monoclonal anti-FLAG M2 (F1804) was from Sigma …
摘要
Lysine-specific histone demethylase 1 (LSD1) modulates chromatin status through demethylation of H3K4 and H3K9. It has been demonstrated that LSD1 is hyperphosphorylated and dissociates from chromatin during mitosis. However, the molecular mechanism of LSD1 detachment is unknown.
Lysine-specific histone demethylase 1 (LSD1) modulates chromatin status through demethylation of H3K4 and H3K9. It has been demonstrated that LSD1 is hyperphosphorylated and dissociates from chromatin during mitosis. However, the molecular mechanism of LSD1 detachment is unknown.