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SFTSV nucleoprotein mediates DNA sensor cGAS degradation to suppress cGAS-dependent antiviral responses

Microbiol Spectr. 2024-05; 
Ze-Zheng Jiang, Min Chu, Li-Na Yan, Wen-Kang Zhang, Bang Li, Jiao Xu, Zhong-Xin Zhao, Hui-Ju Han, Chuan-Min Zhou, Xue-Jie Yu
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Molecular Biology Reagents … The recombinant expression vectors were transfected into HEK293T cells; then, anti-N antibody was purified using a protein A column (GenScript, L00464) and a Superdex 200 column (… Get A Quote

摘要

关键词

RNA virus, SFTSV, autophagy, cGAS, innate immunity, nucleoprotein