![TNF-α, Human (P. Pastoris-expressed) TNF-α, Human (P. Pastoris-expressed)](/product/documents/down?doc_name=Z02682_Activity.jpg&file=scm_files/productFile_notes/2018/04/17/4a5073834aa6ebd41f8bb0e3ba9bba2b.jpg)
ED₅₀<0.08ng/ml, measured in a cytotoxicity assay using L-929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D, corresponding to a specific activity of >1.25 x 10⁷units/mg.
TNF-α, Human (P. pastoris-expressed)
Tumor Necrosis Factor-Alpha (TNF-alpha) plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune diseases. Besides inducing hemorrhagic necrosis of tumors, TNF has been found to be involved in tumorigenesis, tumor metastasis, viral replication, septic shock, fever, inflammation, and autoimmune diseases including Crohn's disease, and rheumatoid arthritis as well as graft-versus-host disease. TNF alpha-1a is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
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Z02682 |
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¥400 |
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联系黄金城集团 |