![PDGF-BB, Human PDGF-BB, Human](/product/documents/down?doc_name=Z02892_SDS-PAGE.png&file=scm_files/productFile_notes/2024/01/19/77385f1d-a9fa-4c89-96a7-dd47a9fa65ac.png)
Lane 1: 2 μg of PDGF-BB, Human, non-reducing (NR)
Lane 2: 2 μg of PDGF-BB, Human, reducing (R)
> 97% as analyzed by SDS-PAGE
PDGF-BB, Human
Platelet-Derived Growth Factor-BB (PDGF-BB) is one of five dimers (PDGF-AA, AB, BB, CC, and DD) formed by 4 different PDGF subunits. In vivo, PDGF-BB is mainly produced in heart and placenta, and predominantly expressed by osteoblasts, fibroblasts, smooth muscle cells, and glial cells. An inactive precursor of PDGF-BB is produced in the endoplasmic reticulum and then activated by a proprotein convertase after secretion. PDGF-BB functions in a paracrine manner and promotes organogenesis, human skeletal development, and wound healing. PDGF-BB also promotes angiogenesis, particularly in the presence of Fibroblast Growth Factor basic. Therefore, PDGF-BB and its related pathways are potential pharmacological targets.
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Z02892 |
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¥1200 |
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联系黄金城集团 |