![IL-9, Human IL-9, Human](/product/documents/down?doc_name=Z03013_Activity.jpg&file=scm_files/productFile_notes/2018/04/17/ff617aabc07a2d7ea0613ef4278880c0.jpg)
ED₅₀< 1 ng/ml, measured in a cell proliferation assay using MO7e cells, corresponding to a specific activity of > 1×10⁶ units/mg.
IL-9, Human
Interleukin 9, also known as IL9, is a cytokine (cell signalling molecule) belonging to the group of interleukins. The protein encoded by this gene is a cytokine produced by T-cells and specifically by CD4+ helper cells that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin-9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
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Z03013 |
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¥600 |
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联系黄金城集团 |