![IL-4 R, Human IL-4 R, Human](/product/documents/down?doc_name=Z03150_Activity.jpg&file=scm_files/productFile_notes/2018/04/17/ced95781f9e196c1366e1368af83d181.jpg)
ED₅₀< 70 ng/ml, measured in a neutralization assay using TF-1 cells in the presence of IL-4,Human(Z02925).
IL-4 R, Human
Interleukin-4 Receptor, also known as IL-4RA and CD124, is a transmembrane glycoprotein belonging to the class I receptor family. It is highly expressed by activated T-cells. IL-4RA couples with γ chain to form the type I receptor for IL-4. The extracellular domain of IL-4RA binds to IL-4 and antagonizes its activity. IL-4RA plays an important role in Th2 cell differentiation, Ig class switching and alternative macrophage activation. It has also been implicated in allergic inflammation, tumor progression and atherogenesis.
|
Z03150 |
|
|
|
|
|
¥700 |
|
|
|
|
联系黄金城集团 |