![PD-1 Fc Chimera, Human PD-1 Fc Chimera, Human](/product/documents/down?doc_name=Z03370_Activity.jpg&file=scm_files/productFile_notes/2018/04/17/df258df89342d86db2c9236eff639740.jpg)
Immobilized PD-L1-His,Human(Cat.No.Z03425) at 2 μg/mL (100 μL/well) can bind PD-1, Fc,Humanwith a linear range of 0.024-0.39μg/mL.
![PD-1 Fc Chimera, Human PD-1 Fc Chimera, Human](/product/documents/down?doc_name=Z03370_Compare To Competitor A.jpg&file=scm_files/productFile_notes/2018/04/17/c5b761ce474ef4749859fb65e76507f2.jpg)
GenScript product showed equal activity compared to competitor A.
PD-1 Fc Chimera, Human
Programmed cell death protein 1, also known as PD-1 and CD279 (cluster of differentiation 279) or PDCD1, is a protein that in humans is encoded by the PDCD1 gene. PD-1 is a cell surface receptor that belongs to the immunoglobulin superfamily and is expressed on T cells and pro-B cells.PD-1 binds two ligands, PD-L1 and PD-L2. PD-1 and its ligands play an important role in down regulating the immune system by preventing the activation of T-cells, which in turn reduces autoimmunity and promotes self-tolerance. The inhibitory effect of PD-1 is accomplished through a dual mechanism of promoting apoptosis (programmed cell death) in antigen specific T-cells in lymph nodes while simultaneously reducing apoptosis in regulatory T cells (suppressor T cells)
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Z03370 |
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¥960 |
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联系黄金城集团 |