![CTLA-4 Fc Chimera, Human CTLA-4 Fc Chimera, Human](/product/documents/down?doc_name=Z03373_Compare To Competitor A_.jpg&file=scm_files/productFile_notes/2018/04/17/04633b403f52bb4f8592c4f3558a80fc.jpg)
GenScript product showed equal activity compared to competitor A when binding with biotin CD80 Fc,Human.
CTLA-4 Fc Chimera, Human
Cytotoxic T lymphocyte-associated molecule-4 (CTLA-4) is a cell surface molecule that is closely related to CD28, and a powerful negative regulator of T cell activation. Structurally, CTLA-4 is a member of the Ig superfamily, having a single extracellular V-like domain , homology with CD28; The overall sequence homology between CD28 and CTLA-4 is about 20%, but they share a 27% (murine) to 31% (human) identity at the amino acid level. Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA-4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
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Z03373 |
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¥520 |
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联系黄金城集团 |