![2B4/CD244 Fc Chimera, Human 2B4/CD244 Fc Chimera, Human](/product/documents/down?doc_name=Z03445_activity.jpg&file=scm_files/productFile_notes/2021/05/24/8e02a6fc-e4c6-4026-b1a7-bea0c4174c54.jpg)
Immobilized SLAMF2 (Mammalian,C-mFc) at 1 µg/ml, 2 µg/ml(100 μl/well) can bind 2B4/CD244 Fc Chimera, Human with EC50=48.56 ng/ml, EC50=75.13 ng/ml when detected by Mouse Anti Human IgG Fc-HRP. Background was subtracted from data points before curve fitting.
2B4/CD244 Fc Chimera, Human
CD244 (Cluster of Differentiation 244) is a human protein encoded by the CD244 gene. It is also known as Natural Killer Cell Receptor 2B4. This gene encodes a cell surface receptor expressed on natural killer cells (NK cells) (and some T cells) mediating non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. CD244 can also be expressed on non-lymphocytes such as eosinophils, mast cells and dendritic cells.
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Z03445 |
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