![FGL1 Fc Chimera, Human FGL1 Fc Chimera, Human](/product/documents/down?doc_name=Z03567_activity.jpg&file=scm_files/productFile_notes/2021/05/24/0922d9cd-f07c-4295-9988-eb5cd759cf01.jpg)
Immobilized h_LAG3 at 5 μg/ml (100 μl/well) can bind FGL1 Fc Chimera, Human with a linear range of 0.097–50 μg/ml when detected by Mouse Anti-Human IgG Fc-HRP. Background was subtracted from data points before curve fitting.
FGL1 Fc Chimera, Human
FGL1 (Fibrinogen-like protein 1), also known as hepatocyte-derived fibrinogen-related protein 1 (HFREP-1), HP-041, hepassocin (HPS), and liver fibrinogen-related protein 1 (LFIRE-1), is a liver-specific secreted protein belonging to the fibrinogen superfamily whose members share a fibrinogen domain at their C-termini. FGL1 is an immune suppressive molecule that inhibits the activation of antigen-specific T cells by acting as a major ligand of LAG3, and binds LAG3 independently of MHC class II.
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Z03567 |
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¥1272 |
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