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目录产品 » CD30/TNFRSF8[Biotin], His & Avi, Human

CD30/TNFRSF8[Biotin], His & Avi, Human

The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153, TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted expression in subpopulations of activated T-and B-cells in nonpathologic conditions. CD30 expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs).
￥5800
 Z04063-100

Species Human
Protein Construction
CD30/TNFRSF8 (Phe19-Lys379)
Accession # P28908-1		 His Avi
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 41.3 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 70-100 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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CD30/TNFRSF8[Biotin], His & Avi, Human

Immobilized Human CD30 Ligand, His Tag at 5 μg/ml (100 μL/well) on the plate. Dose response curve for CD30/TNFRSF8[Biotin], His & Avi, Human, His Tag with the EC50 of 17.5 ng/ml determined by ELISA. »

CD30/TNFRSF8[Biotin], His & Avi, Human

The purity of CD30/TNFRSF8[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC. »

CD30/TNFRSF8[Biotin], His & Avi, Human

CD30/TNFRSF8[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

CD30/TNFRSF8[Biotin], His & Avi, Human

Immobilized Anti-CD30 Antibody, hFc Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for CD30/TNFRSF8[Biotin], His & Avi, Human, His Tag with the EC50 of 10.8 ng/ml determined by ELISA. »

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Target Background The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153, TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted expression in subpopulations of activated T-and B-cells in nonpathologic conditions. CD30 expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs).
Synonyms CD30; CD30KI-1; CD30L receptor; TNFRSF8; D1S166EKi-1; CD30KI-1
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.