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目录产品 » CD27 Ligand/CD70 Trimer, His, Human

CD27 Ligand/CD70 Trimer, His, Human

CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
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 Z04180-100

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Species Human
Protein Construction
His CD27 Ligand/CD70 Trimer (Leu50-Pro193)
Accession # P32970-1
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 51.8 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 62-65 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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CD27 Ligand/CD70 Trimer, His, Human

Immobilized CD27 Ligand/CD70 Trimer, His, Human, His Tag at 2 μg/ml (100 μL/well) on the plate. Dose response curve for Human CD27, hFc Tag with the EC50 of 11.8 ng/ml determined by ELISA. »

CD27 Ligand/CD70 Trimer, His, Human

The purity of CD27 Ligand/CD70 Trimer, His, Human is greater than 95% as determined by SEC-HPLC. »

CD27 Ligand/CD70 Trimer, His, Human

CD27 Ligand/CD70 Trimer, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

CD27 Ligand/CD70 Trimer, His, Human

Immobilized CD27 Ligand/CD70 Trimer, His, Human, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human CD27, hFc Tag with the EC50 of 16.6ng/ml determined by ELISA. »

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Target Background CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
Synonyms CD70 molecule; CD70; TNFSF7; CD27 Ligand; CD27-L; CD27LG; Ki-24 antigen; TNFSF7G
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 For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.