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A compact, low-cost, and binary sensing (BiSense) platform for noise-free and self-validated impedimetric detection of COVID-19 infected patients

Biosens Bioelectron. 2022-06; 
Razieh Salahandish, Pezhman Jalali, Hamed Osouli Tabrizi, Jae Eun Hyun, Fatemeh Haghayegh, Mahmood Khalghollah, Azam Zare, Byron M Berenger, Yan Dong Niu, Ebrahim Ghafar-Zadeh, Amir Sanati-Nezhad
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Proteins, Expression, Isolation and Analysis … The dual biosensing of N-protein in this work was used as a self-validation of the biosensor. … -CoV-2 protein (#Z03488, GenScript Inc.USA) with protein concentrations ranging from 1 pg/… Get A Quote

摘要

Electrochemical immuno-biosensors are one of the most promising approaches for accurate, rapid, and quantitative detection of protein biomarkers. The two-working electrode strip is employed for creating a self-supporting system, as a tool for self-validating the acquired results for added reliability. However, the realization of multiplex electrochemical point-of-care testing (ME-POCT) requires advancement in portable, rapid reading, easy-to-use, and low-cost multichannel potentiostat readers. The combined multiplex biosensor strips and multichannel readers allow for suppressing the possible complex matrix effect or ultra-sensitive detection of different protein biomarkers. Herein, a handheld binary-sensing (Bi... More

关键词

Bi-potentiostat, Electrochemical biosensing, Point-of-care, Rapid tests, SARS-CoV-2