SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that cause illness ranging from the common cold to severe diseases. SARS-CoV-2 Nucleocapsid Protein is derived from SARS-CoV-2, which is associated with nucleic acid. It is a most abundant protein of coronavirus. Because of strong immunogenicity of coronavirus Nucleocapsid, it was believed that SARS-CoV-2 Nucleocapsid Protein has potential value for the diagnosis of the virus.