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🀅 Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formationไ.

ꦬ Sievers SA, Karanicolas J, Chang HW, Zhao A,ℱ Jiang L, Zirafi O, Stevens JT, Münch J, Baker D, Eisenberg D.
🥂 Nature.𓄧 2011 Jun; 475 (7354); 96-100

Immune Self-Reactivity Triggeredও By Drug-Modified Hla-Peptide Repertoire.

Illing PT, Vivian JP, ⭕Dudek NL, Kostenko L, Chen Z, Bharadwaj M, Miles JJ, Kjer-Nielsen L, Gras S, Williamson NA, Burrows SR, Purcell AW, Rossjohn J, McCluskey J.
𓃲 Nature. 2012 Jun; 𝔍

How insulin engages its primaဣry binding site on the insulin receptor.

🦹 John G. Menting, Jonathan Whittaker, Mai B. ♔Margetts, Linda J. Whittaker, Geoffrey K.-W. Kong, + et al.
🌠 Nature. 2013 Jan; ꦓ

Mechanism of Trypanosoma br🍒ucei gambiense resistance to human serum.

Uzureau P, Uzureau S, Lecordier L, Fontaine F, Tebabi P, Homb🔥lÉ F, GrÉlard A, Zhendre V, Nolan DP, Lins L, Crowet JM, Pays A, Felu C, Poelvoorde P, Vanhollebeke B, Moestrup SK, Lyngsø J, Pedersen JS, Mottram JC, Dufourc EJ, PÉrez-Morga D, Pays E. 🥀
🌼 Nature.💞 2013 Aug;

Signal peptides are allosteric activators of the prote𓃲in translocase.

NRMT🌜 is an [agr]-N-methyltransferase that methylates RCC1 and retinoblas♔toma protein.

Tooley CE, Petkowski JJ, Muratore-Schroeder TL, Balsbaugh JL, Shabanowitz J, Saba�🌟�t M, Minor W, Hunt DF, Macara IG.
ཧ Nature. 2010 Aug; 466 (7310); 1125-8 🍸

Cross-neutraꦡlization of influenza A viruses mediated by a single antibody loop.

Ekiert DC, Kashyap AK, Steel J, Rubrum A, Bhabha G, K🐎hayat R, Lee JH, Dillon MA, O'Neil RE, Faynboym AM🙈, Horowitz M, Horowitz L, Ward AB, Palese P, Webby R, Lerner RA, Bhatt RR, Wilson IA.
Nature. 2012 Sep; 489 (7417); 526-32 ꦿ

A peptide deformylase-ribosome complex reveals mechanism of nascent chain processi🏅ng.

Bingel-Erlenmeyer R, Kohler R, Kramer G, Sandikci 🍌A, Antolic S, Maier T, Schaffitzel C, Wiedmann B, Bukau B, Ban N.
Nature. 2008 Apr; 45🍸2 (7183); 108-11

An aspartyl protease directs malar♛ia effector prot𝔉eins to the host cell.

♛ ✱ Boddey JA, Hodder AN, GÜnther S, Gilson PR, Patsiouras H, Kapp EA, Pearce JA, de Koning-Ward TF, Simpson RJ, Crabb BS, Cowman AF.
Natu🌸re. 2010 Feb; 463 (7281); 627-31

A conformat♒ional switch in HP1 releases auto-inhibition to drive heterocꦏhromatin assembly.

Canzio D, ꦦLiao M, Naber N, Pate E, Larson A, Wu S, Marina DB, Garcia JF, Madhani HD, Cooke R, Schuck P, Cheng Y, Narlikar GJ.
Nature. 2013 Apr; 496 (7445); 377-81 🌱

Many X-linked microRNAs escape꧙ meiotic sex chromosome inactivation.

 Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and re🎃lated syndromes.

Valente EM, Logan CV, Mougou-Zerelli S, Lee JH, Silhavy JL, Brancati F, Iannicelli M, Travaglini L, Romani S, Illi B, Adams M, Szymanska K. 查看更多 »Mazzotta❀ A, Lee JE, Tolentino JC, Swistun D, Salpiet😼ro CD, Fede C, Gabriel S, Russ C, Cibulskis K, Sougnez C, Hildebrandt F, Otto EA, Held S, Diplas BH, Davis EE, Mikula M, Strom CM, Ben-Zeev B, Lev D, Sagie TL, Michelson M, Yaron Y, Krause A, Boltshauser E, Elkhartoufi N, Roume J, Shalev S, Munnich A, Saunier S, Inglehearn C, Saad A, Alkindy A, Thomas S, Vekemans M, Dallapiccola B, Katsanis N, Johnson CA, AttiÉ-Bitach T, Gleeson JG.
Nat Genet. 2010 Jul; 42 (7); 619-252 🤡

Reversible active switching of the mechanical properties of a peptide film at🎶 a fluid-fluid interface.

♔ DNA Damage in Oocytes Induces a Switch of the Quality Control Factor TAp63α from Dimer to Tetramer.

Deutsch GB, Zielonka EM, Coutandi⛦n D, Weber TA, Schäfer B, Hannewald J, Luh LM, Durst FG, Ibrahim M, Hoffmann J, Niesen FH, Sentürk A, Kunkel H, Brutschy B, Schleiff E, Knapp S, Acker-Palmer A, Grez M, McKeon F, Dötsch V𒈔.
Cꦐell. 2011 Feb; 144 (4); 566 - 576

ꦗ 𝔍 Order Out Of Disorder: Working Cycle Of An Intrinsically Unfolded Chaperone. 

aPKC Phosphorylation of Bazooka Defines the Apical/Lateral Border in Drosophila; Epithelial Cells.

🔯 Influenza virus M2 protein mediates ESCRT-independent membrane scission.

 Kinetics of antimicrobial peptide activity measured on individual bacterial cells using high-speed atomic force microscopy.🐓 ♈

A novel Minimalist Cell-Free MHC Class II An🦋tigen Processing Sꦚystem Identifies Immunodominant Epitopes. 

Hartman IZ, Kim A, Cotter RJ, Walter K, D🥂alai SK, Boronina T, Griffith W, Lanar DE, Schwenk R, Krzych U, Cole RN❀, Sadegh-Nasseri S.
Nat Med. 201🌞0 Nov; 16 (11); 1333-40