黄金城集团

目录产品 » 重组蛋白 » 趋化因子 » GRO-α/KC/CXCL1, Mouse (CHO-expressed)

GRO-α/KC/CXCL1, Mouse(CHO-expressed)

GRO-α/KC/CXCL1 coded by CXCL1 gene at chromosome 5 is approximately 63% identity to that of mouse MIP2. KC is also approximately 60% identical to the human GROs. Mouse KC is a potent neutrophil attractant and activator. The functional receptor for KC has been identified as CXCR2. Based on the pattern of KC expression in a number of inflammatory disease models, KC appears to have an important role in inflammation. KC was found to be involved in monocyte arrest on atherosclerotic endothelium and may also play a pathophysiological role in Alzheimer’s disease.
Z03141
¥315

联系黄金城集团
Species Mouse
Protein Construction
GRO-α (Ala25-Lys96)
Accession # P12850
Purity > 95% as analyzed by SDS-PAGE
> 95% as analyzed by HPLC
Endotoxin Level < 0.2 EU/μg of protein by gel clotting method
Biological Activity Active at 10.0 ng/ml, measured in a tube formation assay using HUVEC cells.
Expression System CHO
Apparent Molecular Weight 5~7 kDa, on SDS-PAGE under reducing conditions.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

Target Background GRO-α/KC/CXCL1 coded by CXCL1 gene at chromosome 5 is approximately 63% identity to that of mouse MIP2. KC is also approximately 60% identical to the human GROs. Mouse KC is a potent neutrophil attractant and activator. The functional receptor for KC has been identified as CXCR2. Based on the pattern of KC expression in a number of inflammatory disease models, KC appears to have an important role in inflammation. KC was found to be involved in monocyte arrest on atherosclerotic endothelium and may also play a pathophysiological role in Alzheimer’s disease.
Synonyms Growth Regulated Protein/Melanoma Growth Stimulatory Activity; GRO α; MGSA α; CXCL1; NAP-3; GRO1; KC (murine); CINC (rat)

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


喜欢新升级的网站吗?

讨厌

不喜欢

一般

喜欢

非常喜欢

*