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Cowpea polyphenol extract regulates galectin gene expression in bovine blood.

Anim. Biotechnol.. 2019; 
Adjei-FremahSarah,WorkuMulum
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Biochemicals L00350) following the manufacturer’s protocol (GenScript, Piscataway, NJ, USA) as previ- ously described by Adjei-Fremah et al. Get A Quote

摘要

Galectins (GAL) are animal lectins that play important roles in the immune response through regulation of homeostasis and immune function. Bioactive polyphenols are able to bind and regulate galectins in inflammatory diseases. Cowpea is a nutritious and polyphenol-rich legume used as feed. The objective of the study was to evaluate the effect of cowpea polyphenol extract (CPE) on galectin gene transcription and translation in bovine peripheral blood. Blood from lactating cows (?=?10) were treated with CPE (10?μg/mL) or LPS (0.1?μg/mL), and control, to measure mRNA levels of bovine , , , and some innate immune response genes. Secretion of GAL-1, GAL-3 and GAL-9 in plasma were measured using ELISAs.... More

关键词

Galectins,bovine,cowpea polyphenols,immune resp