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Fibrinolytic Changes in Women with Preeclampsia

Clin Appl Thromb Hemost. 1905-07; 
Anne Cathrine Godtfredsen, Johannes Jakobsen Sidelmann, Britta Blume Dolleris, Jan Stener Jørgensen, Emma Kathrine Jungjohan Johansen, Melissa Fernard Bøg Pedersen, Yaseelan Palarasah, Jørgen Brodersen Gram
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Recombinant Proteins … After washing the membrane was incubated with HRP-conjugated streptavidin (GenScript, M00091) PBS-tween. Lastly, a SuperSignal TM West Dura Extended Duration Substrate kit (… Get A Quote

摘要

objective: Preeclampsia (PE) is a serious complication of pregnancy. The fibrinolytic system play crucial roles regarding placentation and evolution of PE. objective: To study comprehensively components of the fibrinolytic system and fibrin lysability in women with PE. methods: 117 women with PE and matched controls were included. Tissue type plasminogen activator (t-PA), plasminogen, PAI-1, plasmin inhibitor (PI), D-dimer, the fibrinolytic potential of dextran sulphate euglobulin fraction (DEF), PAI-2, polymere PAI-2, fibrin clot lysability, thrombin activatable fibrinolysis inhibitor (TAFI) and fibrinogen were assessed. results: Women with PE had significantly increased concentrations of t-PA and PAI-1, where... More

关键词

PAI-2, fibrin lysability, fibrinolysis, preeclampsia, protein polymerization