黄金城集团

至今,GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次,处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果,再次证明GenScript 有能力帮助业内科学家Make research easy.

The Development of a Rabies Virus-Vectored Vaccine against , Targeting BBI39

Vaccines (Basel). 2024-01; 
Shantel Rios, Bibek Bhattachan, Kruthi Vavilikolanu, Chrysoula Kitsou, Utpal Pal, Matthias J Schnell
Products/Services Used Details Operation
Recombinant Proteins … cat#: 16100, Norristown, PA, USA). The GST tag was removed by 80 units of precision protease (GenScript cat#: Z02799, Piscataway, NJ, USA) overnight at 4 C in PCB buffer (50 mM … Get A Quote

摘要

Lyme disease (LD) is the most common tick-borne illness in the United States (U.S.), Europe, and Asia. , a spirochete bacterium transmitted by the tick vector , causes LD in the U.S. If untreated, Lyme arthritis, heart block, and meningitis can occur. Given the absence of a human Lyme disease vaccine, we developed a vaccine using the rabies virus (RABV) vaccine vector BNSP333 and an outer surface borrelial protein, BBI39. BBI39 was previously utilized as a recombinant protein vaccine and was protective in challenge experiments; therefore, we decided to utilize this protective antigen in a rabies virus-vectored vaccine against To incorporate BBI39 into the RABV virion, we generated a chimeric BBI39 antigen, BBI... More

关键词

Borrelia burgdorferi, Lyme disease vaccine, rabies virus, viral vaccine vector