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Identification of IGF2 promotes skin wound healing by co-expression analysis

Int Wound J. 2024-04; 
Xingyan Liu, Ying Teng, Huan Li, Ding Luo, Hongkun Li, Jinghan Shen, Simin Du, Yuyue Zhang, Dali Wang, Jie Jing
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Catalog Antibody … genes in module M8 may have key factors mediating scarless wound healing. Through bioinformatic analysis of genes … analysis using anti-His antibodies (GenScript, Cat. No. A00186). … Get A Quote

摘要

Oral mucosa is an ideal model for studying scarless wound healing. Researchers have shown that the key factors which promote scarless wound healing already exist in basal state of oral mucosa. Thus, to identify the other potential factors in basal state of oral mucosa will benefit to skin wound healing. In this study, we identified eight gene modules enriched in wound healing stages of human skin and oral mucosa through co-expression analysis, among which the module M8 was only module enriched in basal state of oral mucosa, indicating that the genes in module M8 may have key factors mediating scarless wound healing. Through bioinformatic analysis of genes in module M8, we found IGF2 may be the key factor mediat... More

关键词

IGF2, co‐expression analysis, oral mucosa, skin regeneration, wound healing