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The SUMO E3 ligase SIZ1 partially regulates STOP1 SUMOylation and stability in

Plant Signal Behav. 2021-03; 
Qiu Fang, Jie Zhang, Dong-Lei Yang, Chao-Feng Huang
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Catalog Antibody … M2 magnetic beads (M8823, Sigma-Aldrich). The SUMOylated form of STOP1 was detected by using anti Myc-HRP antibody (A00704-100; Genscript Biotech Co., Ltd., China). Evaluation of Al resistance and low Pi response … Get A Quote

摘要

The zinc finger transcription factor STOP1 plays a crucial role in aluminum (Al) resistance and low phosphate (Pi) response. Al stress and low Pi availability do not affect mRNA expression but are able to induce STOP1 protein accumulation by post-transcriptional regulatory mechanisms. We recently reported that STOP1 can be mono-SUMOylated at K40, K212, or K395 sites, and deSUMOylated by the SUMO protease ESD4. SUMOylation of STOP1 is important for the regulation of STOP1 protein function and Al resistance. In the present study, we further characterized the role of the SUMO E3 ligase SIZ1 in STOP1 SUMOylation, Al resistance and low Pi response. We found that mutation of reduced but not eliminated STOP1 SUMOyla... More

关键词

Aluminum resistance, AtALMT1, SIZ1, STOP1, SUMOylation, low phosphate response