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In Vitro Study on Anti-Hepatitis C Virus Activity of Spatholobus suberectus Dunn.

Molecules. 2016-11; 
ChenShao-Ru,WangAn-Qi,LinLi-Gen,QiuHong-Cong,WangYi-Tao,Wang
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Biochemicals … ON, Canada). IFNα-2A (Cat. Z03003-50) was purchased from Genscript (Piscataway Township, NJ, USA). All chemicals were purchased from Cayman Chemical (Ann Arbor, MI, USA) except for those noted otherwise. All other … Get A Quote

摘要

Hepatitis C virus (HCV) infects 200 million people worldwide, and 75% of HCV cases progress into chronic infections, which consequently cause cirrhosis and hepatocellular carcinoma. HCV infection is treated with currently considered standard drugs, including direct anti-viral agents (DAAs), alone or in combination with peginterferon-α plus ribavirin. However, sustained viral responses vary in different cohorts, and high costs limit the broad use of DAAs. In this study, the ethanol and water extracts of 12 herbs from Lingnan in China were examined in terms of their inhibitory effect on HCV replication. Among the examined extracts, ethanol extracts suppressed HCV replication. By comparison, Ex... More

关键词

HCV,S. suberectus extraction,anti-HCV therapy,ta